Osteoactivin Monoclonal / Unconjugated / 303822
Product Details
| Description | Human Osteoactivin/GPNMB Antibody | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | 303822 | |
| Target Species | Human | |
| Applications | ICS, CyTOF, WB, IHC | |
| Supplier | R&D Systems | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About Osteoactivin
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Validation References
| PMID 24425288 | |
|---|---|
| PMID 24589892 | |
| PMID 25889792 | |
| PMID 27642553 | |
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Reviews & Ratings
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