Frizzled-7 Monoclonal / Alexa Fluor 405 / 151143

Product Details
Description Human/Mouse Frizzled-7 Alexa Fluor 405-conjugated Antibody
Conjugate Alexa Fluor 405
Clone 151143
Target Species Human, Mouse
Applications FC
Supplier R&D Systems
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About Frizzled-7
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
About Alexa Fluor 405
Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to V450 (BD Biosciences), Vio®Blue® (Miltenyi Biotec), Cascade Blue® (ThermoFisher Scientific), Pacific Blue® (ThermoFisher Scientific). Alexa 405 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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273 Frizzled-7 antibodies from over 17 suppliers available with over 44 conjugates.

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