Autoimmune Regulator Monoclonal / Alexa Fluor 405 / 609930

Product Details
Description Mouse Autoimmune Regulator/AIRE Alexa Fluor 405-conjugated Antibody
Conjugate Alexa Fluor 405
Clone 609930
Target Species Mouse
Applications ICS
Supplier R&D Systems
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About Autoimmune Regulator
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
About Alexa Fluor 405
Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to V450 (BD Biosciences), Vio®Blue® (Miltenyi Biotec), Cascade Blue® (ThermoFisher Scientific), Pacific Blue® (ThermoFisher Scientific). Alexa 405 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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271 Autoimmune Regulator antibodies from over 18 suppliers available with over 36 conjugates.

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