VEGFR2 Monoclonal / DyLight 755 / EIC

Product Details
Description The monoclonal will detect native human VEGFR-2/ KDR in ELISA experiments and on the surface of different human cell types.
Conjugate DyLight 755
Clone EIC
Target Species Human, Rat
Applications ELISA, FC, ICC, IF, IHC-P, WB, IHC
Supplier Novus Biologicals
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About VEGFR2
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
About DyLight 755
DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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