TIE-1 Monoclonal / DyLight 650 / Cl. 6F12

Product Details
Description The monoclonal antibody will detect native human TIE-1 in ELISA experiments and on the surface of different human cell types.
Conjugate DyLight 650
Clone Cl. 6F12
Target Species Human
Applications ELISA, FC, WB
Supplier Novus Biologicals
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About TIE-1
This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
About DyLight 650
DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications.
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364 TIE-1 antibodies from over 17 suppliers available with over 45 conjugates.

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