RUNX3 Monoclonal / DyLight 488 / K12P3F11*C9

Product Details
Description Mouse RUNX3/CBFA3 antibody [DyLight 488] reacts with Human
Conjugate DyLight 488
Clone K12P3F11*C9
Target Species Human
Applications ELISA, WB, IHC
Supplier Novus Biologicals
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About RUNX3
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
About DyLight 488
DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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