PCNA Monoclonal / DyLight 650 / PC10

Product Details
Description Specific for PCNA p36 protein expressed at high levels in proliferating cells.
Conjugate DyLight 650
Clone PC10
Target Species Chicken, Drosophila, Fish, Human, Mouse, Porcine, Primate, Rabbit, Rat, Yeast, Zebrafish
Applications ELISA, FC, ICC, IF, IHC-P, WB, IHC-Fr, IHC
Supplier Novus Biologicals
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About PCNA
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
About DyLight 650
DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications.
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