OPTN Polyclonal / Unconjugated /

Product Details
Description The Anti-Optineurin antibody from GeneTex is a Rabbit Polyclonal antibody to Optineurin. The Anti-Optineurin antibody Recognizes Human, Mouse. The Anti-Optineurin antibody has been validated for the following Applications: ICC/IF, WB, IHC-P.
Conjugate Unconjugated
Clone
Target Species Human, Mouse
Applications ICC, IF, IHC-P, WB
Supplier GeneTex
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About OPTN
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
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