DNASE2B Polyclonal / Unconjugated /
Product Details
Description | The Anti-DNASE2B antibody [N1C3] from GeneTex is a Rabbit Polyclonal antibody to DNASE2B. The Anti-DNASE2B antibody [N1C3] Recognizes Human. The Anti-DNASE2B antibody [N1C3] has been validated for the following Applications: ICC/IF, WB. | |
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Conjugate | Unconjugated | |
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Target Species | Human | |
Applications | ICC, IF, WB | |
Supplier | GeneTex | |
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About DNASE2B
The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
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