CD11b Monoclonal / Unconjugated / 5C6
Product Details
Description | The Anti-CD11b antibody [5C6] (Low endotoxin, azide free) from GeneTex is a Rat Monoclonal antibody to CD11b. The Anti-CD11b antibody [5C6] (Low endotoxin, azide free) Recognizes Human, Mouse. The Anti-CD11b antibody [5C6] (Low endotoxin, azide free) has been validated for the following Applications: FACS, ICC/IF, IHC-Fr, IP, Functional Assay. | |
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Conjugate | Unconjugated | |
Clone | 5C6 | |
Target Species | Human, Mouse | |
Applications | FC, ICC, IF, Functional, IHC-Fr | |
Supplier | GeneTex | |
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About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
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