TM4SF1/L6 Monoclonal / Biotin / REA851

Product Details

Description	Clone REA851 recognizes the human TM4SF1 antigen, also known as transmembrane 4 L6 family member 1. TM4SF1 is a member of the tetraspanin family, which members are involved in signal transduction events, important for the regulation of cell development, activation, growth, and motility. It is reported, that TM4SF1 suppresses the expression of CD63 and CD82, two molecules that inhibit cell mobility. TM4SF1 is highly expressed in lung, breast, colon, and ovarian carcinomas. It is also found on some endothelial cells. \| Additional information: Clone REA851 displays negligible binding to Fc receptors.
Conjugate	Biotin
Clone	REA851
Target Species	Human
Applications	FC
Supplier	Miltenyi Biotec
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About TM4SF1/L6
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008]

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