JAML Monoclonal / APC / REA862

Product Details

Description	Clone REA862 recognizes the mouse JAML antigen, also known as AMICA1 or junctional adhesion molecule-like protein. JAML is a transmembrane protein, which consists of two extracellular immunoglobulin-like domains, a membrane-spanning region, and a cytoplasmic tail involved in activation signaling. JAML is found on gamma/delta intraepithelial T cells. The costimulatory molecule JAML binds to its ligands Coxsackie virus and adenovirus receptor (CAR), that leads to cellular proliferation and cytokine and growth factor production. \| Additional information: Clone REA862 displays negligible binding to Fc receptors.
Conjugate	APC
Clone	REA862
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
	Catalog #	Sign in to view product details, citations, and spectra
	Size
	Price
	Antigen
	Host
	Isotype

About JAML
Enables integrin binding activity and protein homodimerization activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and myeloid leukocyte migration. Located in bicellular tight junction; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.

Experiment Design Tools