HLA A3 Monoclonal / PE / REA950

Product Details
Description Clone REA950 recognizes the human major histocompatibility complex (MHC) class I molecule HLA-A3, a heterodimer belonging to the HLA-A family and consisting of two subtypes, A3.1 and A3.2. HLA-A has a heavy chain (anchored in the membrane) and a light chain (beta-2 microglobulin). MHC class I molecules are expressed on nearly all nucleated cells and present small intracellular peptides on the cell surface to the immune system. The peptids are recognized by circulating CD8+ cytotoxic T lymphocytes. | Additional information: Clone REA950 displays negligible binding to Fc receptors.
Conjugate PE
Clone REA950
Target Species Human
Applications FC
Supplier Miltenyi Biotec
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About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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Validation References
PMID 2456340
PMID 11705846
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44 HLA A3 antibodies from over 5 suppliers available with over 31 conjugates.

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