CD98 Monoclonal / FITC / REA861

Product Details
Description Clone REA861 recognizes the mouse CD98 antigen, also known as 4F2. CD98 is a disulfide-linked heterodimeric cell-surface glycoprotein which plays a role in cellular activation and proliferation and is involved in the regulation of the amino acid transport system. CD98 is found at high levels in adult testis, lung, brain, kidney, and spleen, and at significantly lower levels in skeletal muscle, adult liver, and cardiac. | Additional information: Clone REA861 displays negligible binding to Fc receptors.
Conjugate FITC
Clone REA861
Target Species Mouse
Applications FC
Supplier Miltenyi Biotec
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About FITC
Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.
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Validation References
PMID 2928113
PMID 10391915
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