CD8b.2 Monoclonal / APC-Vio770 / REA865

Product Details

Description	Clone REA865 recognizes the beta chain of the mouse CD8 antigen, a single-pass type I membrane protein also known as lymphocyte antigen 3 (Ly-3.2 or Lyt-3.2). The CD8 molecule is composed of two distinct polypeptide chains that pair on the cell surface either as a CD8 alphaalpha homodimer or as a CD8 alphabeta heterodimer. These forms of the CD8 molecule are differentially expressed on functionally distinct CD8+ lymphocyte subsets. The CD8 alphabeta heterodimer is expressed on cytotoxic T cells and thymocytes. CD8b functions as a co-receptor for the T cell receptor (TCR). \| Additional information: Clone REA865 displays negligible binding to Fc receptors.
Conjugate	APC-Vio770
Clone	REA865
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
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About APC-Vio770
APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.

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