CD45RC Monoclonal / VioBright 515 / REA1000

Product Details
Description Clone REA1000 recognizes the RC isoform of the rat CD45 antigen, also known as leukocyte common antigen (LCA), which is a single-chain type I transmembrane glycoprotein. CD45 has multiple isoforms and differential glycosylation, CD45RC is the high molecular weight form of CD45. CD45 is expressed at high levels on all cells of hematopoietic origin except for erythrocyte and platelets. It plays a role in signal transduction through B and T cell antigen receptors. The CD45RC isoform is expressed on B cells, most cytotoxic T cells, and a subset of T helper cells, but not expressed on myeloid cells. | Additional information: Clone REA1000 displays negligible binding to Fc receptors.
Conjugate VioBright 515
Clone REA1000
Target Species Rat
Applications FC
Supplier Miltenyi Biotec
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About VioBright 515
Vio®Bright® B515 from Miltenyi has an excitation peak at 488 nm and an emission peak at 514. It is comparable to BB515 in flow cytometry.
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Validation References
PMID 374095
PMID 2960606
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