CD45RC Monoclonal / PE / REA1000

Product Details

Description	Clone REA1000 recognizes the RC isoform of the rat CD45 antigen, also known as leukocyte common antigen (LCA), which is a single-chain type I transmembrane glycoprotein. CD45 has multiple isoforms and differential glycosylation, CD45RC is the high molecular weight form of CD45. CD45 is expressed at high levels on all cells of hematopoietic origin except for erythrocyte and platelets. It plays a role in signal transduction through B and T cell antigen receptors. The CD45RC isoform is expressed on B cells, most cytotoxic T cells, and a subset of T helper cells, but not expressed on myeloid cells. \| Additional information: Clone REA1000 displays negligible binding to Fc receptors.
Conjugate	PE
Clone	REA1000
Target Species	Rat
Applications	FC
Supplier	Miltenyi Biotec
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About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

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