CLEC9A Monoclonal / Biotin / REA976
Product Details
Description | Clone REA976 recognizes the human CD370 antigen, also known as C-type lectin domain family 9 member A (CLEC9A). CD370 is a type II transmembrane glycoprotein member of 241 amino acids with a predicted molecular mass of ~30 kDa. It is also known as DNGR-1 and is expressed on BDCA-3+ myeloid dendritic cells from peripheral blood and lymphoid tissues. CD370 acts as a receptor for necrotic cells and plays an important role in cross-presentation. | Additional information: Clone REA976 displays negligible binding to Fc receptors. | |
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Conjugate | Biotin | |
Clone | REA976 | |
Target Species | Human | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
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About CLEC9A
CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008]
CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008]
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Validation References
PMID 18497879 | |
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PMID 19219027 | |
PMID 20479117 | |
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