Siglec-6 Monoclonal / Biotin / REA852
Product Details
| Description | Clone REA852 recognizes the human CD327 antigen, which is also known as sialic acid binding Ig-like lectin 6 (Siglec-6), belonging to the Ig superfamily that is involved in cell-cell interactions and signaling. As an adhesion molecule, CD327 mediates sialic acid dependent interaction to cells by binding to the alpha-2,6-linked sialic acid and is highly expressed in placenta and at low levels in spleen, peripheral blood leukocytes, and small intestine. | Additional information: Clone REA852 displays negligible binding to Fc receptors. | | |
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| Conjugate | Biotin | |
| Clone | REA852 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About Siglec-6
This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia. [provided by RefSeq, Jul 2016]
This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia. [provided by RefSeq, Jul 2016]
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Validation References
| PMID 7782275 | |
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| PMID 10428856 | |
| PMID 12655776 | |
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