CD31 Monoclonal / VioBright 515 / REA1028

Product Details

Description	Clone REA1028 recognizes the human CD31 antigen, a 120–140 kDa single-chain transmembrane glycoprotein, which is present on virtually all monocytes, platelets, and granulocytes. CD31 is also expressed by lymphocyte subsets. During maturation of CD4+ T cells, the expression of CD31 changes: CD4+ recent thymic emigrants (RTEs) express CD31 in contrast to central naive T cells. CD31 is highly expressed on endothelial cells, especially at their juncture, and is also known EndoCAM. \| Additional information: Clone REA1028 displays negligible binding to Fc receptors.
Conjugate	VioBright 515
Clone	REA1028
Target Species	Human
Applications	FC
Supplier	Miltenyi Biotec
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About CD31
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]

About VioBright 515
Vio®Bright® B515 from Miltenyi has an excitation peak at 488 nm and an emission peak at 514. It is comparable to BB515 in flow cytometry.

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