NGF Receptor p75 Monoclonal / VioBlue / REA844

Product Details
Description Clone REA844 recognizes the human CD271 antigen, also known as low-affinity nerve growth factor receptor (LNGFR) or p75 neurotrophin receptor (NTR). CD271 belongs to the low-affinity neurotrophin receptors and the tumor necrosis factor receptor superfamily. Initially the human CD271 (LNGFR) was described to be expressed on cells of the central and peripheral nervous system and was suggested to be involved in the development, survival, and differentiation of cells. | Expression of CD271 (LNGFR) is found on mesenchymal stem/stromal cells (MSCs), follicular dendritic cells, mesenchymal cells involved in mesenchymal-epithelial interactions, autonomic and sensory neurons, oligodendrocytes, astrocytes, schwann cells, and neural crest stem cells. | Additional information: Clone REA844 displays negligible binding to Fc receptors.
Conjugate VioBlue
Clone REA844
Target Species Human
Applications FC
Supplier Miltenyi Biotec
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About NGF Receptor p75
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]
About VioBlue
Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec).
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