CD2 Monoclonal / Biotin / REA959
Product Details
| Description | Clone REA959 recognizes the type I transmembrane glycoprotein CD2, also known as LFA-2 or Ly-37. In mouse, CD2 is expressed on all lymphocytes except a subpopulation of intraepithelial T lymphocytes. It is a major receptor for CD48 and is involved in activation and differentiation of T cells. CD2-mediated cell-cell adhesion can be blocked by REA959. | Additional information: Clone REA959 displays negligible binding to Fc receptors. | |
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| Conjugate | Biotin | |
| Clone | REA959 | |
| Target Species | Mouse | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
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About CD2
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016]
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016]
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Validation References
| PMID 1700989 | |
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| PMID 2463634 | |
| PMID 8871350 | |
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