CD158e Monoclonal / VioBright 515 / REA1005
Product Details
Description | Clone REA1005 recognizes the human CD158e (KIR3DL1), a member of the killer immunoglobulin-like receptor (KIR) family expressed on CD56dimCD16+ natural killer (NK) cells and CD8+ T cells. KIRs contribute to the regulation of NK cell–mediated cytotoxicity. They are monomeric receptors possessing high allelic polymorphism with either 2 or 3 Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be further subdivided into inhibitory KIRs and activating KIRs (KIR2DS or KIR3DS). KIR3DL1 provides an inhibitory signal of NK cell lytic activity upon interaction with its specific ligand, HLA-Bw4. | Additional information: Clone REA1005 displays negligible binding to Fc receptors. | |
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Conjugate | VioBright 515 | |
Clone | REA1005 | |
Target Species | Human | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
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About VioBright 515
Vio®Bright® B515 from Miltenyi has an excitation peak at 488 nm and an emission peak at 514. It is comparable to BB515 in flow cytometry.
Vio®Bright® B515 from Miltenyi has an excitation peak at 488 nm and an emission peak at 514. It is comparable to BB515 in flow cytometry.
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Validation References
PMID 9059894 | |
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PMID 11895890 | |
PMID 12200350 | |
PMID 12493005 | |
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85 CD158e antibodies from over 8 suppliers available with over 20 conjugates.