CD11a/CD18 Monoclonal / Biotin / REA880
Product Details
Description | Clone REA 880 recognizes the CD11a/CD18 heterodimer, also known as lymphocyte function–associated antigen 1 (LFA-1). LFA-1 is a member of the integrin family and consists of two chains, a (CD11a) and b2 (CD18). It is expressed on T and B cells as well as on macrophages and neutrophils. LFA-1 plays an essential role in the immune system, e.g., in leukocyte adhesion by interaction with ICAM-1 and ICAM-2, in cytotoxic T cell–mediated killing, antibody-dependent killing by granulocytes and monocytes, and in T cell proliferation. | Additional information: Clone REA880 displays negligible binding to Fc receptors. | |
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Conjugate | Biotin | |
Clone | REA880 | |
Target Species | Mouse | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
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Validation References
PMID 2051027 | |
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PMID 7576051 | |
PMID 16234355 | |
PMID 21245485 | |
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