MDC1 Monoclonal / ATTO 633 / P2B11

Product Details
Description Mouse Anti-Mouse MDC1 Monoclonal IgG1
Conjugate ATTO 633
Clone P2B11
Target Species Bovine, Chimpanzee, Human, Mouse
Applications ICC, IF, WB
Supplier Stressmarq
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About MDC1
The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq, Jul 2008]
About ATTO 633
ATTO 633 from ATTO-Tec Gmbh has an excitation peak at 629 nm and an emission peak at 657 nm.
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