SNAP25 Monoclonal / Unconjugated / SP-12

Product Details
Description Mouse Anti-Human SNAP-25 Monoclonal IgG1
Conjugate Unconjugated
Clone SP-12
Target Species Feline, Human, Mouse, Porcine, Rat
Applications ELISA, IF, ICC, WB, IHC
Supplier Stressmarq
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About SNAP25
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
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