Wilm's Tumor 1 Monoclonal / CF680R / WT1/857

Product Details
Description Wilm's Tumor 1 / WT1 Monoclonal Mouse Antibody (WT1/857)
Conjugate CF680R
Clone WT1/857
Target Species Human, Mouse, Rat
Applications FC, Immunohistology - Formalin, IF
Supplier Biotium
Catalog # Sign in to view product details, citations, and spectra
Size
Price
Antigen
Host
Isotype
About Wilm's Tumor 1
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Mar 2015]
About CF680R
CF®680R from Biotium is a fluorophore with an excitation peak at 680 nm and an emission peak at 701 nm. It can be useful in both fluorescence microscopy and flow cytometry. For microscopy, CF®680R has been specifically validated in super-resolution imaging by STORM, STED and 2-Photon microscopy. It is spectrally similar to Alexa Fluor™ 680, IRDye® 680 and Cy5.5.
Experiment Design Tools
Panel Builders

Looking to design a Microscopy or Flow Cytometry experiment?

Validation References
Additional
Sources
Reviews & Ratings
Looking for more options?

781 Wilm's Tumor 1 antibodies from over 26 suppliers available with over 51 conjugates.

Supplier Page
 Compare