About CD86
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]

About CF680R
CF®680R from Biotium is a fluorophore with an excitation peak at 680 nm and an emission peak at 701 nm. It can be useful in both fluorescence microscopy and flow cytometry. For microscopy, CF®680R has been specifically validated in super-resolution imaging by STORM, STED and 2-Photon microscopy. It is spectrally similar to Alexa Fluor™ 680, IRDye® 680 and Cy5.5.