p57Kip2 Monoclonal / Biotin / KIP2/880
Product Details
| Description | p57 / KIP2 Monoclonal Mouse Antibody (KIP2/880) | |
|---|---|---|
| Conjugate | Biotin | |
| Clone | KIP2/880 | |
| Target Species | Human, Mouse | |
| Applications | FC, IF, IHC-P | |
| Supplier | Biotium | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About p57Kip2
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
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552 p57Kip2 antibodies from over 22 suppliers available with over 50 conjugates.
