NOX4 Monoclonal / CF640R / NOX4/1245

Product Details
Description NOX4 / NADPH-Oxidase-4 Monoclonal Mouse Antibody (NOX4/1245)
Conjugate CF640R
Clone NOX4/1245
Target Species Human
Applications ELISA, FC, IF, WB
Supplier Biotium
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About NOX4
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
About CF640R
CF®640R from Biotium is a fluorophore with an excitation peak at 642 nm and an emission peak at 662 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 647, DyLight™ 649 and Cy5.
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