MALT1 Monoclonal / CF680R / MT1/410
Product Details
Description | MALT-1 Monoclonal Mouse Antibody (MT1/410) | |
---|---|---|
Conjugate | CF680R | |
Clone | MT1/410 | |
Target Species | Human | |
Applications | FC, IF, IHC-P, WB | |
Supplier | Biotium | |
Catalog # | Sign in to view product details, citations, and spectra | |
Size | ||
Price | ||
Antigen | ||
Host | ||
Isotype |
About MALT1
This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2018]
This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2018]
About CF680R
CF®680R from Biotium is a fluorophore with an excitation peak at 680 nm and an emission peak at 701 nm. It can be useful in both fluorescence microscopy and flow cytometry. For microscopy, CF®680R has been specifically validated in super-resolution imaging by STORM, STED and 2-Photon microscopy. It is spectrally similar to Alexa Fluor™ 680, IRDye® 680 and Cy5.5.
CF®680R from Biotium is a fluorophore with an excitation peak at 680 nm and an emission peak at 701 nm. It can be useful in both fluorescence microscopy and flow cytometry. For microscopy, CF®680R has been specifically validated in super-resolution imaging by STORM, STED and 2-Photon microscopy. It is spectrally similar to Alexa Fluor™ 680, IRDye® 680 and Cy5.5.
Experiment Design Tools
Panel Builders
Looking to design a Microscopy or Flow Cytometry experiment?
Validation References
Reviews & Ratings
Reviews |
---|
Looking for more options?
416 MALT1 antibodies from over 22 suppliers available with over 50 conjugates.