MALT1 Monoclonal / CF555 / MT1/410
Product Details
Description | MALT-1 Monoclonal Mouse Antibody (MT1/410) | |
---|---|---|
Conjugate | CF555 | |
Clone | MT1/410 | |
Target Species | Human | |
Applications | FC, IF, IHC-P, WB | |
Supplier | Biotium | |
Catalog # | Sign in to view product details, citations, and spectra | |
Size | ||
Price | ||
Antigen | ||
Host | ||
Isotype |
About MALT1
This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2018]
This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2018]
About CF555
CF®555 from Biotium is a fluorophore with an excitation peak at 555 nm and an emission peak at 565 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 555, ATTO 550 and DyLight™ 550. In Flow Cytometry, R-PE is a brighter alternative to CF®555. In microscopy, it has been validated for use in super-resolution imaging by STORM.
CF®555 from Biotium is a fluorophore with an excitation peak at 555 nm and an emission peak at 565 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 555, ATTO 550 and DyLight™ 550. In Flow Cytometry, R-PE is a brighter alternative to CF®555. In microscopy, it has been validated for use in super-resolution imaging by STORM.
Experiment Design Tools
Panel Builders
Looking to design a Microscopy or Flow Cytometry experiment?
Validation References
Reviews & Ratings
Reviews |
---|
Looking for more options?
416 MALT1 antibodies from over 22 suppliers available with over 50 conjugates.