Cytokeratin 8 Monoclonal / CF568 / K8.8

Product Details
Description Cytokeratin 8 Monoclonal Mouse Antibody (K8.8)
Conjugate CF568
Clone K8.8
Target Species Human
Applications FC, IF, IHC-P
Supplier Biotium
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About Cytokeratin 8
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
About CF568
CF®568 from Biotium is a fluorophore with an excitation peak at 562 nm and an emission peak at 583 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 568 and ATTO 565. However, in flow cytometry, a superior alternative is R-PE. In microscopy, CF®568 is validated in super-resolution imaging by STORM, STED, Structured Illumination (SIM) and TIRF.
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1591 Cytokeratin 8 antibodies from over 31 suppliers available with over 53 conjugates.

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