CD162 Monoclonal / CF543 / PSGL1/1601
Product Details
Description | CD162 Monoclonal Mouse Antibody (PSGL1/1601) | |
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Conjugate | CF543 | |
Clone | PSGL1/1601 | |
Target Species | Human | |
Applications | FC, IF, IHC-P | |
Supplier | Biotium | |
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About CD162
This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
About CF543
CF®543 from Biotium is a fluorophore with an excitation peak at 541 nm and an emission peak at 560 nm. It can be useful in both fluorescence microscopy and flow cytometry.
CF®543 from Biotium is a fluorophore with an excitation peak at 541 nm and an emission peak at 560 nm. It can be useful in both fluorescence microscopy and flow cytometry.
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776 CD162 antibodies from over 31 suppliers available with over 86 conjugates.