Caldesmon HMW Monoclonal / CF488A / CALD1/820 h-CALD

Product Details
Description Caldesmon, HMW Monoclonal Mouse Antibody (CALD1/820 + h-CALD)
Conjugate CF488A
Clone CALD1/820 h-CALD
Target Species Human
Applications FC, IF, IHC-P
Supplier Biotium
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About Caldesmon HMW
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
About CF488A
CF®488A from Biotium is a fluorophore with an excitation peak at 490 nm and an emission peak at 515 nm. It is spectrally similar to Fluorescein, Alexa Fluor™ 488 and DyLight™ 488. It can be use in fluorescence microscopy and flow cytometry. In microscopy, CF®488A has been specifically validated for STORM, STED, Structured Illumination (SIM), 2-Photon microscopy and TIRF.
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166 Caldesmon HMW antibodies available with over 18 conjugates.

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