alpha-Methylacyl-CoA Racemase Monoclonal / CF680 / AMACR/1723
Product Details
Description | AMACR / p504S Monoclonal Mouse Antibody (AMACR/1723) | |
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Conjugate | CF680 | |
Clone | AMACR/1723 | |
Target Species | Human | |
Applications | IF, IHC-P | |
Supplier | Biotium | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About alpha-Methylacyl-CoA Racemase
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
About CF680
CF®680 from Biotium is a fluorophore with an excitation peak at 681 nm and an emission peak at 698 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 680, IRDye® 680 and Cy5.5.
CF®680 from Biotium is a fluorophore with an excitation peak at 681 nm and an emission peak at 698 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 680, IRDye® 680 and Cy5.5.
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