PMEL17 Monoclonal / CF647 / NKI-beteb

Product Details
Description Pmel17 / gp100 / SILV Monoclonal Mouse Antibody (NKI-beteb)
Conjugate CF647
Clone NKI-beteb
Target Species Equine, Human
Applications FC, IF, IHC-P
Supplier Biotium
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About PMEL17
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]
About CF647
CF®647 from Biotium is a fluorophore with an excitation peak at 642 nm and an emission peak at 662 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 647, DyLight™ 649 and Cy5.
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726 PMEL17 antibodies from over 17 suppliers available with over 44 conjugates.

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