About Transgelin
This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization. [provided by RefSeq, Aug 2017]

About CF680R
CF®680R from Biotium is a fluorophore with an excitation peak at 680 nm and an emission peak at 701 nm. It can be useful in both fluorescence microscopy and flow cytometry. For microscopy, CF®680R has been specifically validated in super-resolution imaging by STORM, STED and 2-Photon microscopy. It is spectrally similar to Alexa Fluor™ 680, IRDye® 680 and Cy5.5.