C-Myc Monoclonal / CF680 / MYC699

Product Details
Description c-Myc Monoclonal Mouse Antibody (MYC699)
Conjugate CF680
Clone MYC699
Target Species Chimpanzee, Gorilla, Human
Applications FC, IF
Supplier Biotium
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About C-Myc
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
About CF680
CF®680 from Biotium is a fluorophore with an excitation peak at 681 nm and an emission peak at 698 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 680, IRDye® 680 and Cy5.5.
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