Neurofilament Heavy 200kDa Monoclonal / CF405S / NF421 NFL/736

Product Details
Description Neurofilament Monoclonal Mouse Antibody (NF421 + NFL/736)
Conjugate CF405S
Clone NF421 NFL/736
Target Species Chicken, Human, Mouse, Porcine, Rat
Applications FC, IHC-P
Supplier Biotium
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About Neurofilament Heavy 200kDa
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
About CF405S
CF®405S from Biotium is a fluorophore with an excitation peak at 404 nm and an emission peak at 431 nm. It is spectrally similar to Alexa Fluor™ 405. It can be use in fluorescence microscopy, specifically its been validated in Structured Illumination (SIM), and flow cytometry. However, in flow cytometry, superior alternatives are Brilliant™ Violet 421, SuperNova v428 and StarBright Violet 440.
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1185 Neurofilament Heavy 200kDa antibodies from over 31 suppliers available with over 54 conjugates.

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