HUWE1 / Unconjugated / AX8D1
Product Details
| Description | HECTH9 (AX8D1) Mouse mAb recognizes endogenous levels of total HECTH9 protein. | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | AX8D1 | |
| Target Species | Human, Monkey, Mouse, Rat | |
| Applications | WB | |
| Supplier | Cell Signaling Technology | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About HUWE1
This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic cognitive disability. [provided by RefSeq, Aug 2013]
This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic cognitive disability. [provided by RefSeq, Aug 2013]
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104 HUWE1 antibodies from over 16 suppliers available with over 22 conjugates.
