TRADD / Unconjugated / 7G8
Product Details
| Description | TRADD (7G8) Rabbit mAb detects endogenous levels of total TRADD protein. | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | 7G8 | |
| Target Species | Human | |
| Applications | WB, IP | |
| Supplier | Cell Signaling Technology | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About TRADD
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
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334 TRADD antibodies from over 23 suppliers available with over 37 conjugates.
