PSMA3 / Unconjugated / D4Y9O

Product Details
Description PSMA3 (D4Y9O) Rabbit mAb recognizes endogenous levels of total PSMA3 protein. This antibody does not cross-react with other α subunits of the 20S proteasome. This antibody cross-reacts with a 140 kDa protein of unknown identity in lysates from certain cell lines.
Conjugate Unconjugated
Clone D4Y9O
Target Species Canine, Equine, Human, Monkey, Mouse, Porcine, Rat
Applications WB, IP
Supplier Cell Signaling Technology
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About PSMA3
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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