NEDD4 / Unconjugated / D82F4
Product Details
| Description | NEDD4 (D82F4) Rabbit mAb detects endogenous levels of total NEDD4. The antibody does not cross react with NEDD4L. | |
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| Conjugate | Unconjugated | |
| Clone | D82F4 | |
| Target Species | Equine, Human, Monkey, Rat | |
| Applications | WB, IP | |
| Supplier | Cell Signaling Technology | |
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About NEDD4
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016]
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016]
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181 NEDD4 antibodies from over 21 suppliers available with over 40 conjugates.
