MSH2 / Unconjugated /
Product Details
Description | MSH2 (D24B5) XP® Rabbit mAb detects endogenous levels of total MSH2 protein. | |
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Conjugate | Unconjugated | |
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Target Species | Human, Mouse | |
Applications | FC, IF, IHC-P, WB, IP | |
Supplier | Cell Signaling Technology | |
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About MSH2
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
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