Jagged 1 / Unconjugated / 1C4

Product Details
Description Jagged1 (1C4) Rabbit mAb detects endogenous level of total Jagged1 protein. It does not cross-react with Jagged2.
Conjugate Unconjugated
Clone 1C4
Target Species Human
Applications WB
Supplier Cell Signaling Technology
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About Jagged 1
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Nov 2019]
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