Dkk-2 / Unconjugated / G44

Product Details
Description DKK2 (G44) Antibody detects transfected levels of human DKK2 protein. This antibody does not cross-react with DKK1.
Conjugate Unconjugated
Clone G44
Target Species Human
Applications WB
Supplier Cell Signaling Technology
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About Dkk-2
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008]
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