CD3 epsilon / violetFluor 450 /
Product Details
| Description | CD3 (UCHT1) Mouse mAb (violetFluor™ 450 Conjugate) recognizes endogenous levels of total CD3ε, CD3γ, and CD3δ proteins. This antibody detects epitopes within both the extracellular and intracellular domains of CD3ε. | |
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| Conjugate | violetFluor 450 | |
| Clone | ||
| Target Species | Human | |
| Applications | FC | |
| Supplier | Cell Signaling Technology | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD3 epsilon
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
About violetFluor 450
VioletFluor® 450 is a fluorophore from Tonbo with an excitation peak at 405 nm and an emission peak at 450 nm.
VioletFluor® 450 is a fluorophore from Tonbo with an excitation peak at 405 nm and an emission peak at 450 nm.
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1076 CD3 epsilon antibodies from over 30 suppliers available with over 66 conjugates.
