CD31 / Brilliant Violet 480 / L133.1

Product Details
Description BV480 Mouse Anti-Human CD31
Conjugate Brilliant Violet 480
Clone L133.1
Target Species Human
Applications FC
Supplier BD Biosciences
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About CD31
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]
About Brilliant Violet 480
Brilliantâ„¢ Violet 480 (BV480) is a green-emitting non-tandem polymer fluorophore that can be excited by the 405 nm Violet laser and collected using a 525/40 bandpass filter. BV480 has an excitation peak at 436 nm and an emission peak at 478 nm, and provides an optimized alternative to BV510. Other dyes that are similar include StarBright Violet 475 (Bio-Rad) While BV480 can be detected on the same filter as BV510, its emmision profile reduces spillover into the BV605, BV650, and BV711 channels. Additionally BV480's excitation profile will reduce cross-laser excitation with the UV laser, resulting in less spillover into UV channels than BV510. These advantages make BV480 an optimal choice for flow cytometry panels using multiple reagents on Violet and/or UV lasers. This dye is part of the Brilliantâ„¢ Violet dye line. BV510 and BV480 are the only dyes in the Brilliantâ„¢ Violet dye family that are not tandem fluorophores based off the BV421 polymer core, but they have nearly the same maximum excitation.
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