CD11b / Brilliant Blue 700 / M1/70
Product Details
Description | BB700 Rat Anti-CD11b | |
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Conjugate | Brilliant Blue 700 | |
Clone | M1/70 | |
Target Species | Human, Mouse | |
Applications | FC | |
Supplier | BD Biosciences | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
About Brilliant Blue 700
Horizon Brilliantâ„¢ Blue 700 (BB700) from BD Biosciences is a tandem dye of BB515. It has an excitation peak at 484 nm and an emission peak at 695 nm, making it spectrally comparable to PerCP-Cy5.5.
Horizon Brilliantâ„¢ Blue 700 (BB700) from BD Biosciences is a tandem dye of BB515. It has an excitation peak at 484 nm and an emission peak at 695 nm, making it spectrally comparable to PerCP-Cy5.5.
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